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Fast Deprotection RNA Phosphoramidites

Proligo® Reagents

Product Breadth of Proligo Reagents
Standard Phosphoramidites
Green Arrow  DNA and RNA Pharmadite®
Green Arrow  DNA Phosphoramidite
Green Arrow  2'O-TC RNA Phosphoramidite
Green Arrow  2'O-TBDMS RNA Phosphoramidite
Green Arrow  2'O-Methyl Phosphoramidite
Green Arrow  2'Fluoro Phosphoramidite
Green Arrow  5'-NPPOC DNA Phosphoramidite
Green Arrow  Non-Standard Nucleosides Phosphoramidite

Fast Deprotection Chemistry (FD)
Green Arrow  FD DNA Phosphoramidite
Green Arrow  2'O-TBDMS RNA Phosphoramidite
Supports
Green Arrow  Bulk Controlled Pore Glass (CPG)
 DNA CPG
 RNA CPG
 Amino-ON CPG
 Universal CPG

Columns
Green Arrow  DNA CPG Column
Green Arrow  RNA CPG Column
Green Arrow  DNA Polystyrene Column
Labels and Modifications
Green Arrow  6-FAM
Green Arrow  Fluorescein Phosphoramidite
Green Arrow  Biotin Phosphoramidite
Green Arrow  Phosphate-ON

Linkers
Green Arrow  MMT and TFA Amino Linker
Green Arrow  ssH Linker

Solvents
Green Arrow  Liquid Reagents
Green Arrow  Activator 42®

RNA Phosphoramidites with Fast Deprotection Chemistry  
   
   
  Download Literature:
  •  User Instructions
Fast Deprotecton RNA Phosphoramidites
(770k pdf)
  View Structure:
  •  rA(tac) Phosphoramidite
  •  rC(tac) Phosphoramidite
  •  rG(tac) Phosphoramidite
  •  rU Phosphoramidite

SAFC Proligo Reagents offers RNA phosphoramidite monomers with Fast Deprotection Chemistry (tert-butylphenoxyacetyl (TAC) group).
Advantages of synthesis with TAC-protected RNA phosphoramidites

Increased synthesis yield and reduced purification efforts

Dramatically reduced deprotection times

Minimized exposure to alkaline deprotection medium

Minimized chain degradation during deprotection
   

RNA Phosphoramidites
Compatible with Expedite™ and Polygen® Instruments
Product No. Description Unit
A212081-01 DMT-2′-O-TBDMS-rA(tac) amidite 1 x 0.5g
C212081-01 DMT-2′-O-TBDMS-rC(tac) amidite 1 x 0.5g
G212081-01 DMT-2′-O-TBDMS-rG(tac) amidite 1 x 0.5g
U211081-01 DMT-2′-O-TBDMS-rU amidite 1 x 0.5g
Compatible with ABI™ Instruments
Product No. Description Unit
A212031-01 DMT-2′-O-TBDMS-rA(tac) amidite 1 x 0.5g
A212061-01 DMT-2′-O-TBDMS-rA(tac) amidite 1 x 1 g
C212031-01 DMT-2′-O-TBDMS-rC(tac) amidite 1 x 0.5g
C212061-01 DMT-2′-O-TBDMS-rC(tac) amidite 1 x 1 g
G212031-01 DMT-2′-O-TBDMS-rG(tac) amidite 1 x 0.5g
G212061-01 DMT-2′-O-TBDMS-rG(tac) amidite 1 x 1 g
U211031-01 DMT-2′-O-TBDMS-rU amidite 1 x 0.5g
U211061-01 DMT-2′-O-TBDMS-rU amidite 1 x 1 g
  Other quantities and packaging are available upon request.

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