Contact SAFC   Extranet
SAFC Global
 

Non-standard Nucleosides

Proligo® Reagents

Product Breadth of Proligo Reagents
Standard Phosphoramidites
Green Arrow  DNA and RNA Pharmadite®
Green Arrow  DNA Phosphoramidite
Green Arrow  2'O-TC RNA Phosphoramidite
Green Arrow  2'O-TBDMS RNA Phosphoramidite
Green Arrow  2'O-Methyl Phosphoramidite
Green Arrow  2'Fluoro Phosphoramidite
Green Arrow  5'-NPPOC DNA Phosphoramidite
Green Arrow  Non-Standard Nucleosides Phosphoramidite

Fast Deprotection Chemistry (FD)
Green Arrow  FD DNA Phosphoramidite
Green Arrow  2'O-TBDMS RNA Phosphoramidite
Supports
Green Arrow  Bulk Controlled Pore Glass (CPG)
 DNA CPG
 RNA CPG
 Amino-ON CPG
 Universal CPG

Columns
Green Arrow  DNA CPG Column
Green Arrow  RNA CPG Column
Green Arrow  DNA Polystyrene Column
Labels and Modifications
Green Arrow  6-FAM
Green Arrow  Fluorescein Phosphoramidite
Green Arrow  Biotin Phosphoramidite
Green Arrow  Phosphate-ON

Linkers
Green Arrow  MMT and TFA Amino Linker
Green Arrow  ssH Linker

Solvents
Green Arrow  Liquid Reagents
Green Arrow  Activator 42®

Several applications of synthetic oligonucleotides are based on nucleosides with alternative heterocycles. SAFC Proligo Reagents provides phosphoramidites of selected non-standard nucleosides as catalogue items and offers custom synthesis services for proprietary monomers.  
   
   
  Download Literature:
  •  User Instructions
MMT-Amino Linker Phosphoramidite
(657k pdf)
  •  User Instructions
TFA-Amino Linker Phosphoramidite
(656k pdf)
  View Structure:
  •  MMT-Amino
hexanol-ß-
Cyanoethyl
phosphoramidite
  •  Trifluoroacetyl-
Aminopentanol-
ß-Cyanoethyl
phosphoramidite
   
Non-Standard Nucleosides
Compatible with Expedite™ and Polygen® Instruments
Product No. Description Unit
M010282-01 MMT-hexylamine-linker amidite 1 x 0.25g
M010682-01 TFA pentylaminolinker amidite 1 x 0.25g
M010882-01 TFA Hexylaminolinker Amidite 1 x 0.25g
Compatible with ABI™ Instruments
M010232-01 MMT-hexylamine-linker amidite 1 x 0.25g
M010632-01 TFA pentylaminolinker amidite 1 x 0.25g
M010832-01 TFA Hexylaminolinker Amidite 1 x 0.25g
Custom Products Phosphoramidites of non-catalogue linkers, reporters or modifiers are offered as custom synthesis products. Please enquire.

Custom Products
Phosphoramidites of alternative nucleosides (DNA, RNA or modified RNA) are offered as custom synthesis products. Please inquire.
 

SAFC and Proligo are registered trademarks of Sigma-Aldrich Co. LLC.
©2012 Sigma-Aldrich Co. LLC. All rights reserved. Reproduction forbidden without permission.
Other trademarks are the property of their respective owners.

To order or speak with a Customer Service Representative, contact your local SAFC office.