Since Merrifield first described solid phase synthesis, researchers have investigated numerous supports for the chemical synthesis of DNA. Controlled Pore Glass (CPG) has proven to be the most accepted standard, with features such as high surface area, efficient mass transfer and chemical inertness.

Because the pore density of CPG can be adjusted, the solid support can be tailored to the size of the synthetic oligonucleotide required. Bigger pore size is typically preferable in minimizing steric effects during the synthesis of long oligonucleotides, while smaller pore size fosters improved synthesis consistency.

Our process guarantees consistent production of CPGs to specifications designed for DNA synthesis.

All products are tested in our Quality Control labs for purity and identity prior to release. SAFC Proligo Reagent's facility in Hamburg, Germany is ISO 9001 certified.

On this Page
	DNA CPG
	Fast deprotection DNA CPG

DNA CPG

Analytical Parameters of CPG
	CPG (UHL)	CPG 500Å	CPG 1000Å
Pore size (nm)	33	50	100
Pore volume (ml/g)	1.3	1.3	1.3
Grain size (µm)	100 - 180	100 – 180	100 - 180
Surface (m²/g)	~100	~60	~30

Nucleoside-Loaded CPG
	Loading µmol/g
CPG 500Å	30-40
CPG 1000Å	25-35
CPG UHL	50-70
CPG UHL	90-110

DNA Controlled Pore Glass
Product No.	Description	Unit
	DNA CPG 500 Å, 30-40 μmol/g
A301001-01	dA(bz)-CPG	1 g
A301010-01	dA(bz)-CPG	10 g
C301001-01	dC(bz)-CPG	1 g
C301010-01	dC(bz)-CPG	10 g
G301001-01	dG(ib)-CPG	1 g
G301010-01	dG(ib)-CPG	10 g
T301001-01	dT-CPG	1 g
T301010-01	dT-CPG	10 g

	DNA CPG 1000 Å, 25-35 μmol/g
A401001-01	dA(bz)-CPG	1 g
A401010-01	dA(bz)-CPG	10 g
C401001-01	dC(bz)-CPG	1 g
C401010-01	dC(bz)-CPG	10 g
G401001-01	dG(ib)-CPG	1 g
G401010-01	dG(ib)-CPG	10 g
T401001-01	dT-CPG	1 g
T401010-01	dT-CPG	10 g

	DNA CPG UHL, 50-70 μmol/g
A503001-01	dA(bz)-CPG	1 g
A503010-01	dA(bz)-CPG	10 g
C503001-01	dC(bz)-CPG	1 g
C503010-01	dC(bz)-CPG	10 g
G503001-01	dG(ib)-CPG	1 g
G503010-01	dG(ib)-CPG	10 g
T503001-01	dt-CPG	1 g
T503010-01	dt-CPG	10 g

	DNA CPG UHL, 90-110 μmol/g
A501010-01	dA(bz)-CPG	10 g
C501010-01	dC(bz)-CPG	10 g
G501010-01	dG(ib)-CPG	10 g
T501010-01	dt-CPG	10 g
Custom Products	Bulk packaging up to multiple kg per container and customized packaging with alternative quantities of amidites are available upon request.

Fast deprotection DNA CPG

Fast Deprotection CPG
Product No.	Description	Unit
A302001-01	CPG 500Å, dA(tac), 30-40 μmol/g	1 x 1g
C302001-01	CPG 500Å, dC(tac), 30-40 μmol/g	1 x 1g
G302001-01	CPG 500Å, dG(tac), 30-40 μmol/g	1 x 1g
A402001-01	CPG 1000Å, dA(tac), 25-35 μmol/g	1 x 1g
C402001-01	CPG 1000Å, dC(tac), 25-35 μmol/g	1 x 1g
G402001-01	CPG 1000Å, dG(tac), 25-35 μmol/g	1 x 1g
C302010-01	CPG 500Å, dC(tac), 30-40 μmol/g	1 x 10g
C402010-01	CPG 500Å, dC(tac), 25-35 μmol/g	1 x 10g
G305001-01	CPG 500Å, dG(tac), 30-40 μmol/g	1 x 1g
G305010-01	CPG 500Å, dG(tac), 30-40 μmol/g	1 x 10g

SAFC and Proligo are registered trademarks of Sigma-Aldrich Co. LLC.
©2012 Sigma-Aldrich Co. LLC. All rights reserved. Reproduction forbidden without permission.
Other trademarks are the property of their respective owners.

To order or speak with a Customer Service Representative, contact your local SAFC office.