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2'O-TC RNA Phosphoramidite
Product Breadth of Proligo Reagents
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SAFC TC RNA Phosphoramidites
SAFC extends its robust Proligo® Reagents portfolio with the new TC RNA Phosphoramidite product line. Developed by Agilent Technologies and distributed through SAFC, these highly regarded, innovative monomers allow for faster, more efficient RNA based oligo manufacturing and the potential to build longer RNA oligos (>100 bases). TC RNA Phosphoramidites streamline the deprotection process resulting in consistently high quality products, offering time and cost savings.
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| Reduced coupling time 3 minutes with ETT Activator 0.25M compared to 15 minutes of TBDMS RNA |
| High coupling efficiency |
| One-step downstream process with neat Ethylenediamine |
| Cleavage and deprotection within 2hours at ambient temperature |
| No need of any fluoride component |
| No need for desalting of oligos required |
| Enables manufacturing of long RNA oligomers |
| High yields of final oligo, best results have been archived using a buffer system |

SAFC is committed to this technology and provides these Phosphoramidites at unequalled purity and quality.
| Ordering Information |
| TC RNA Phosphoramidites |
| Compatible with ABI™/ÄKTA® |
| Product No. |
Description |
Unit |
| A211630-0.5G |
DMT-2'O-TC-rA(bz) Phosphoramidite |
1 x 0.5G |
| C213630-0.5G |
DMT-2'O-TC-rC(ac) Phosphoramidite |
1 x 0.5G |
| G211630-0.5G |
DMT-2'O-TC-rG(ib) Phosphoramidite |
1 x 0.5G |
| U211630-0.5G |
DMT-2'O-TC-rU Phosphoramidite |
1 x 0.5G |
| A211630-1G |
DMT-2'O-TC-rA(bz) Phosphoramidite |
1 x 1G |
| C213630-1G |
DMT-2'O-TC-rC(ac) Phosphoramidite |
1 x 1G |
| G211630-1G |
DMT-2'O-TC-rG(ib) Phosphoramidite |
1 x 1G |
| U211630-1G |
DMT-2'O-TC-rU Phosphoramidite |
1 x 1G |
| Compatible with Expedite™ |
| A211680-0.5G |
DMT-2'O-TC-rA(bz) Phosphoramidite |
1 x 0.5G |
| C213680-0.5G |
DMT-2'O-TC-rC(ac) Phosphoramidite |
1 x 0.5G |
| G211680-0.5G |
DMT-2'O-TC-rG(ib) Phosphoramidite |
1 x 0.5G |
| U211680-0.5G |
DMT-2'O-TC-rU Phosphoramidite |
1 x 0.5G |
| A211680-1G |
DMT-2'O-TC-rA(bz) Phosphoramidite |
1 x 1G |
| C213680-1G |
DMT-2'O-TC-rC(ac) Phosphoramidite |
1 x 1G |
| G211680-1G |
DMT-2'O-TC-rG(ib) Phosphoramidite |
1 x 1G |
| U211680-1G |
DMT-2'O-TC-rU Phosphoramidite |
1 x 1G |
| Compatible with MerMade |
| Product No. |
Description |
Unit |
| A211640-1G |
DMT-2'O-TC-rA(bz) Phosphoramidite |
1 x 1G |
| C213640-1G |
DMT-2'O-TC-rC(ac) Phosphoramidite |
1 x 1G |
| G211640-1G |
DMT-2'O-TC-rG(ib) Phosphoramidite |
1 x 1G |
| U211640-1G |
DMT-2'O-TC-rU Phosphoramidite |
1 x 1G |
TC RNA phosphoramidites and it use is protected by pending US Patent applications Nos. 12/118,655; 12/466326; 61/099,131 and corresponding foreign counterparts, including those issuing from PCT/US08/63342 and PCT/US09/057922. A license may be required.
SAFC and Proligo are registered trademarks of Sigma-Aldrich Co. LLC. ©2012 Sigma-Aldrich Co. LLC. All rights reserved. Reproduction forbidden without permission. Other trademarks are the property of their respective owners.
To order or speak with a Customer Service Representative, contact your local SAFC office.
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