|
Biocides & Preservatives
ProClin® Biocides
Security and Simplicity in your IVD kit manufacturing process
|
Reduce complexity in your IVD kit manufacturing process with ready to use
liquid solution in fit for use package sizes |
|
Increase risk mitigation with guaranteed preservative raw materials and full
regulatory documentation package |
ProClin Product list
ProClin key features
ProClin Mechanism of Action
ProClin Premium Quality
All ProClin products are now premium quality grade, in order to better meet your
evolving regulatory needs.
Click here for more information on the SAFC enhanced quality program.
| Key features of ProClin preservatives |
|
Compatibility with key enzymes and assay indicators |
|
Will not inhibit antibody binding |
|
Easy-to-use water-soluble liquid, effective at very low concentrations |
|
Excellent stability over a wide pH range |
|
Level of active ingredients assayable by HPLC (Inquire for a HPLC standard) |
|
At recommended usage levels, ProClin presents no health hazards, toxological problems or disposal issues |
ProClin Features
| Features |
ProClin 150 |
ProClin 200 |
ProClin 300 |
ProClin 950 |
| Active (A.I.) |
CMIT/MIT |
CMIT/MIT |
CMIT/MIT |
MIT |
| % total A.I. |
1.5 |
1.5 |
3 |
9.5 |
| Stabilizers |
23 – 25% Mg salts |
3% Mg & Cu salts |
Alkyl Carboxylate |
none |
| Matrix |
Water |
Water |
Propylene Glycol |
Water |
| Working pH Range |
2.5 – 8.5 |
2.5 – 8.5 |
2.5 – 8.5 |
2 – 12 |
Typical Dosage Levels
(w/w) |
0.05 – 0.10% |
0.05 – 0.10% |
0.03 – 0.05% |
0.05 – 0.10% |
| Specific Gravity |
1.20 |
1.02 |
1.03 |
1.02 |
| Shelf Life |
4 years |
18 months |
3 years |
3 years |
 Mechanism of Action
The active components of ProClin are three isothiazolones, 2-Methyl-4-isothiazolin-3-one, 5-Chloro-2-methyl-4-isothiazolin-3-one and 1,2-Benzisothiazolin-3-one.
Within minutes of contacting a microorganism, the active components penetrate the cell wall and inhibit specific enzymes (at the points noted in red in the Krebs Cycle).
Growth, macromolecule synthesis and respiration are inhibited, ultimately leading to cell death.
Biocides for other applications
SAFC and Sigma-Aldrich has a wide range of biocide products available for a applications ranging from research to product development and manufacturing.
Biocides Product list
|
