cGMP Biazzi Hydrogenation

Complex Technologies

Hydrogenation and Biazzi Hydrogenator

SAFC® has expertise in Hydrogenations. From small scale hydrogenation development and cGMP production up to 800L, we have established processes to ensure equivalence in all scales of production.

One of the cornerstones of this offer is our 800L Biazzi hydrogenator. Biazzi technology has the capability to greatly enhance reaction efficiency reducing the overall time and costs associated with this process. Throughout development and manufacture, all process critical parameters are recorded, trended and retained reactions.

Biazzi Advantage

	400 Liter nominal working volume to 720 Liter maximum capacity
	Excellent heat and mass transfer facilitates fast reaction times
	Provides a high level of process control regarding pressure and temperature parameters - cooling rates of up to 7°C per minute can be achieved
	Ability to re-use catalyst for multiple batches
	Sampling possible at high pressure
	The Biazzi and catalyst filter are C22 Hastelloy providing excellent material compatibility.
	cGMP design includes a Clean-in-Place (CIP) Hydrogenation and Biazzi Hydrogenator
	50 barg maximum working pressure
	+15°C to +150°C operating temperature range