SAFC's Buchs, Switzerland facility specializes in complex, multi-step organic custom synthesis of pre-registered APIs and key intermediates from Phase I to Phase III clinical trials. This cGMP, ISO certified site provides a wide range of development and production capabilities, including Simulated Moving Bed (SMB) chromatography and micro-reactor technology.
Working in close alignment with other SAFC global facilities, the Buchs site offers its customers the quality, dependability and flexibility to move their products to market quickly and efficiently.
>> SAFC Buchs – Facility
Capabilities Overview
Buchs offers a broad range of multi-purpose manufacturing capabilities and is a proven contract manufacturing (CMO) partner that accelerates the development process.
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Over 30 vessels, up to 1,600 L capacity |
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Temperature range: -65 to +200 °C |
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Three rotary evaporators (50 L) |
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3 centrifuges (1 stainless steel, 2 Hastelloy®) |
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Two distillation stills (100 and 250 L) |
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Two thin-film evaporators |
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Small-scale chiral (SMB) separation unit |
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Chemistry Development Services
Buchs chemists are known for their ability to solve chemistry challenges and develop efficient chemical processes that support customers programs.
Comprehensive development services including: |
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Seven Ph.D. process development chemists |
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Specialized technologies proven to reduce development times |
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- Chem-EYE (FT-IR in-line monitoring system) |
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- Automated lab reactors |
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- Micro-reactor technology |
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- SMB capabilities |
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Proficiency in scaling-up processes targeted for large-scale manufacturing |
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