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Pharmorphix® Analytical Services
Solid State Technology Analytical Services
In addition to supporting our more in-depth solid form programs, both the analytical and physico-chemical property services are available to our clients for both one off and regular requirements. All data produced is of the highest quality and can be supplied to our clients in customized format along with any expert comments or recommendations.
Through its Pharmorphix brand, SAFC® provides a comprehensive toolbox of analytical and solid state equipment that is operated by highly trained pharmaceutical scientists.
| Diffraction Studies: |
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Single crystal X-ray diffraction (SXD) studies for structure determination and absolute stereochemistry determination for regulatory submission. |
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Microcrystal diffraction techniques for structure elucidation of small crystalline fragments less than 50 microns. |
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X-ray powder diffraction (XRPD) studies including variable temperature (VT) and variable relative humidity (VRH) controlled environments. |
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Structure determination from powder diffraction data. |
| Structure elucidation: |
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1H and 13C NMR spectroscopy (400 MHz), IR, Raman |
| Thermal Methods: |
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Differential Scanning Calorimetry (DSC) |
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Modulated DSC (mDSC) |
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Thermogravimetric Analysis (TGA) |
| Moisture Sorption: |
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Gravimetric vapour sorption (GVS / DVS) |
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Static Incubator studies |
| Bulk Properties Determination: |
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Particle sizing |
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Tap bulk density |
| Microscopy: |
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Optical |
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SEM |
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Hot-stage |
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