Expertise in Downstream Purification

Vaccines

Customizing Reagents to Fit Your Downstream Processes

A history of continual collaboration with the world's largest vaccine manufacturers has enabled us to develop a wide range of vaccine technologies-from mammalian cells and bacterial-based systems to egg-based systems. This expertise allows us to provide consistent supply of cGMP products:

	Powder blends for hydration at customer facilities to save time and minimize weighing of multiple components
	Ready-to-use liquid formulations to increase capacity
	Concentrates for in-line dilution and/or reduction of storage volumes

Downstream Processing and Reagents

Single-Use Disposable Systems

SAFC® and biodisposable industry leader Sartorius Stedim Biotech have partnered to offer an outstanding single-use disposable system. Strenghs are combined in: filtration, liquid handling, development/manufacturing of cell culture media and downstream purification. The resulting disposable lab covers: custom solution creation, validation support, process improvement, technical support and problem solving.

Our in-house manufacturing services include cGMP grade custom packaged media or buffers, validation support, process improvement, technical support and troubleshooting.

Stimulate Productivity with Purified Chromatography Resins

SAFC can offer ready-to-use, sterile, endotoxin-free adsorbent capsules for purifying biological preparations therefore extending life of chromatography resins and improving product purity. SAFC manufactures Porozorb adsorbent capsules using Amberlite® XAD-4 and Amberlite XAD-16 resins, key to products purification for current world leaders in vaccines manufacturing. Porozorb is highly effective in adsorbing relatively low molecular weight and water-soluble organic compounds from aqueous systems.

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