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SAFC Global
 

Jerusalem, Israel


Site Overview
SAFC® Jerusalem, Israel Manufacturing Site
Jerusalem is SAFC's newest contract manufacturing fermentation facility. The 50,000 sq. ft. state-of-the-art Biosafety Level 2 facility has been designed to meet both EU and FDA compliance standards for large-scale cGMP production of fermentation-derived biologic products and small organic molecules. Highly experienced scientific teams can provide a complete range of services, including process evaluation and development, optimization and scale up, technology transfer, cGMP manufacturing, analytical testing and regulatory filing.

This new facility underlines SAFC's commitment to support customers at every stage of the drug development pipeline.


Contact Jerusalem
13, Kiryat Hamada Street
Har Hotzvim
Jerusalem 97770
Israel

Tel: ++-972-2589-3632
Fax: ++-972-2582-7474


Adobe PDF
For more information,
view the Jerusalem
facility insert

(284 Kb PDF).




Core Technologies Core Competencies
Yeast Fermentation High Potent Fermentation derived products
Fungi Fermentation Recombinant Proteins
Bacterial Fermentation including streptomyces Secondary Metabolites
  Natural Proteins
  Cell Wall Components
Capabilities/Equipment Overview
The Jerusalem site can provide a complete range of state-of-the-art fermentation, downstream processing and purification capabilities including:
Customized master and working cell banks of natural or recombinant microorganisms, including Risk Group 2 (RG2) pathogens
Sourced bacterium, streptomycetes, filamentous fungi or yeast for fermentation
Wide range of fermentation capacity (100 L, 1,000 L, and 4,000 L fermentors)
Downstream processing and final purification using contained equipment
Clean In Place (CIP) and Sterilization or Steam In Place (SIP) fermenters and other relevant equipment
Jacketed and/or explosion proof equipment
Continuous disc stack and high speed centrifuges
Processing vessels up to 4,000 L
Liquid-liquid extraction column (200 L)
Evaporation train (550 L)
Cross flow ultra/diafiltration
Fast Protein Liquid Chromatography (FPLC)
Medium Pressure Liquid Chromatography (MPLC)
Freeze dryer (Lyophilization)

Certificates and Documents
FDA Registration 3003126415
ISO 9001:2000 Certificate (1.76 mb PDF)