Chinese Hamster Ovary (CHO) cell lines continue to be the predominant cell line of choice for biopharmaceutical manufacturers. SAFC’s CHOZN products and services were created utilizing zinc finger nuclease (ZFN) technology to engineer CHO cell lines with characteristics that are attractive to biopharmaceutical developers and manufacturers, such as growth, productivity and stability.
Visit the pages below to learn more about these novel cell lines and other capabilities, and find out how they can help you take your molecule to clinic faster.
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CHOZN® Platform
Powered by the CompoZr® Zinc Finger Nuclease (ZFN) technology, SAFC has created the first ever commercially available cell line platform that allows for faster, simpler selection and scale up of high producing clones for the production of recombinant protein drugs. The combination of SAFC's robust CHOZN GS cell line, growth and production media, feed and application protocols are designed to seamlessly take users from transfection to small scale bioreactor runs, thus decreasing time to market.
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CHOZN® ZFN-modified CHO cell lines for Bioproduction
A robust cell line that maintains favorable growth and productivity characteristics is the foundation for biopharmaceutical companies to develop a platform production process, thus enabling regulatory acceptance and commercial consistency.
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CHOZN® Cell Design Studio
The CHOZN® Cell Design Studio team is familiar with the needs and concerns specific to biopharmaceutical customers. This custom cell line engineering service includes project management support from inquiry to project completion, documentation of cell handling, and full traceability of raw materials.
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CompoZr® Zinc Finger Nucleases
Zinc Finger Nuclease (ZFN) technology allows easy creation of novel CHO cell lines with precise and heritable gene additions, deletions or modifications.
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Download information about our CHOZN products
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